Global Blood Resources  

Autologous Blood Management at its Best

The Hemobag
 

Blood conservation and management

INDEX: General | Blood substitutes | News | Papers | Associations & organizations

General 

The truth about transfusions PBS Video. (16 August 2010)

Evidence in favor of bloodless surgery mounts

Blood products should be used conservatively in heart-surgery patients, trial shows (28 Oct. 2009)

10 Facts About Blood Transfusions That Every Physician, Nurse, Perfusionist & Hospital Executive Should Know

Blood transfusion and outcomes - International panel of experts finds little evidence for transfusions improving health (23 April 2009)

Soon, all eyes on better blood use (CAP Today, Dec. 2008)

Anemia and surgery: From the preoperative period to postoperative recovery (National Anemia Action Council , 3 Dec. 2008)

Anemia can help body heal, study finds (11 Aug. 2008)

Bloodless surgery clears way for better care (14 July 2008)

Fewer transfusions lowers costs, helps patient (5 May 2008)

Blood myths (NSW Govt., Australia)

  • Myth 1: "Blood, it's safer than it's ever been"
  • Myth 2: "A blood transfusion will get my patient home sooner"
  • Myth 3: "Blood transfusions improve healing"
  • Myth 4: "Autologous blood (pre-donated) is risk-free"
  • Myth 5: "Blood, it's free anyway"

TrasylolR in the news

Blood substitutes

Northfield Laboratories, maker of Polyheme, folds business (15 May 2009)

Battle to be better than blood (14 Jan. 2009)

US Navy to trial Hemopure Stabilized Hemoglobin (11 Dec. 2008)

Results of blood substitute trial show no survival advantage to trauma patients (25 Oct. 2007)

Biopure seeks compassionate use protocol for treatment of acute anemia (24 Aug. 2007)

Northfield Laboratories turns into a zombie (Polyheme) (23 May 2007)

How artificial blood works (howstuffworks.com)

Blood Management

Joint Commission: Blood Management Performance Measures Project - Last Updated 10/09

Routine use of anemia drugs in cancer patients risky: reviews (30 Apr. 2009)

NATA: Transfusion Alternatives in Transfusion Medicine: TOC - Current journal

Safety and Effectiveness of Two Blood Transfusion Strategies in Surgical Patients With Cardiovascular Disease (FOCUS) (clinicaltrials.gov)

AABB, ARC, ABC: Joint Statement Before the Advisory Committee on Blood Safety and Availability, May 30, 2008: Clinical Significance of Red Cell Age in Transfusions

PDFOlder Red Cells - BEST Collaborative view of the evidence (presentation to U.S. Dept of HHS Advisory Committee on Blood Safety & Availability, 30 May 2008 - 55 slides)

PDF BEST Collaborative responds to recent studies purporting to show that transfusion of older red blood cells leads to greater risk (press release, 27 May 2008)

Restrictive blood transfusion does not worsen clinical outcome (online CME/CE activity)

Isbister J. PDF From transfusion to patient blood management (72-slide presentation)

Treating patients like Jehovah's Witnesses could save lives: experts say (28 May 2007)

Taking a harder line on blood transfusions (CAP Today, May 2007)

FDA strengthens safety information for erythropoiesis-stimulating agents (9 Mar. 2007)

Predictor of mortality In cardiac patients found by researchers

Blood transfusions should be used in moderation for acute coronary syndrome (Duke University study)

Intra-operative cell salvage (online CE courses from UK)

Doctors question whether all blood transfusions are effective and necessary. Br Med J  2005 Mar12;330:558.

 SABM Reference Library

Transfusion Alert: Use of Autologous Blood (National Heart, Lung, and Blood Institute)

Transfusion brings experts' blood to a boil (The Australian, 16 June 2007)

US heart patients receive more transfusions than international patients (Medical News Today, 18 Nov. 2005)

 Blood management papers

Anemia Management and Blood Conservation in the Hospital Setting (CME/CE)

Agarwal MB. The ideal transfusion trigger in critically ill patients. Indian J Crit Care Med [serial online] 2007 [cited 2008 Jan 13 ;11:173-5.

Alghamdi AA, Albanna MJ, Guru V, Brister SJ. Does the use of erythropoietin reduce the risk of exposure to allogeneic blood transfusion in cardiac surgery? A systematic review and meta-analysis. J Card Surg 2006 May-Jun;21(3):320-6.

Barone J, et al. Blood doping in the surgical intensive care unit: evidence-based surgical rebuttal. Surgery. 2007 Jan;141(1):7-8

Beckmann SR, Carlile D, Bissinger RC, Burrell M, Winkler T, Shely WW. Improved coagulation and blood conservation in the golden hours after cardiopulmonary bypass. J Extra Corpor Technol 2007 Jun;39(2):103-8.

Bennett J, Haynes S, Torella F, Grainger H, McCollum C. Acute normovolemic hemodilution in moderate blood loss surgery: a randomized controlled trial. Transfusion 2006 Jul;46(7):1097-103.

Brandt MM, Rubinfeld I, Jordan J, Trivedi D, Horst HM. Transfusion insurgency: practice change through education and evidence-based recommendations. Am J Surg 2009 Mar;197(3):279-83.

Bursi F, Barbieri A, Politi L, Di Girolamo A, Malagoli A, Grimaldi T, et al. Perioperative red blood cell transfusion and outcome in stable patients after elective major vascular surgery. Eur J Vasc Endovasc Surg 2008 Dec 24. [Epub ahead of print]

Cardone D, Klein AA. Perioperative blood conservation. Eur J Anaesthesiol. 2009 May 14.

Carless P, Henry D, Moxey A, O'connell D, Brown T, Fergusson D. Cell salvage for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev. 2006 Oct 18;4:CD001888.

Ciurea SO, Hoffman R. Cytokines for the treatment of thrombocytopenia. Semin Hematol 2007 Jul; 44(3):166-82.

Donat R Spahn DR, Marcucci C. Blood management in intensive care medicine: CRIT and ABC – what can we learn? Crit Care. 2004; 8(2): 89–90.

Ela Y, Emmiler M, Kocogullari CU, Terzi Y, Sivaci RG, Cekirdekci A. Advantages of autologous blood transfusion in off-pump coronary artery bypass. Heart Surgery Forum 2009 Oct;12(5): E261 - E265.

Feltracco P, Michieletto E, Barbieri S, Serra E, Rizzi S, Salvaterra F, Cillo U, Ori C. Microbiologic contamination of intraoperative blood salvaged during liver transplantation. Transplant Proc. 2007 Jul-Aug;39(6):1889-91.

Fergusson DA, McIntyre L. The future of clinical trials evaluating blood substitutes. JAMA 2008 May 21;299(19):2324-6. Epub 2008 Apr 28.

Fliser D, Haller H. Erythropoietin and treatment of non-anemic conditions-cardiovascular protection. Semin Hematol 2007 Jul;44(3):212-7.

Freedman J, Luke K, Monga N, Lincoln S, Koen R, Escobar M, Chiavetta J. A provincial program of blood conservation: The Ontario Transfusion Coordinators (ONTraC). Transfus Apher Sci 2005 Nov;33(3):343-9.

Gerber DR. Transfusion of packed red blood cells in patients with ischemic heart disease. Crit Care Med. 2008 Apr;36(4):1068-74

Gould S, Cimino MJ, Gerber DR. Packed red blood cell transfusion in the intensive care unit: limitations and consequences. Am J Crit Care. 2007 Jan;16(1):39-48. 

Karger R, Kretschmer V. Modern concepts of autologous haemotherapy. Transfus Apheresis Sci 2005 Apr;32(2):185-96.

Klein AA, Nashef SA, Sharples L, Bottrill F, Dyer M, Armstrong J, Vuylsteke A. A randomized controlled trial of cell salvage in routine cardiac surgery. Anesth Analg 2008 Nov;107(5):1487-95.

Kristeller JL, Stahl RF, Roslund BP, Roke-Thomas M. Aprotinin use in cardiac surgery patients at low risk for requiring blood transfusion. Pharmacotherapy. 2007 Jul;27(7):988-94.

Lee LY, DeBois WJ, Krieger KH, Isom OW. Transfusion therapy and blood conservation. In: Cohn LH, Edmunds LH Jr, eds. Cardiac surgery in the adult. New York: McGraw-Hill, 2003:389-400. (Table of Contents)

Maglish Ehrman BL, Moore HA. Blood conservation strategies in cardiovascular surgery. Dimens Crit Care Nurs 2004 Nov/Dec; 23(6): 244-52.

Moonen AF, Knoors NT, van Os JJ, Verburg AD, Pilot P. Retransfusion of filtered shed blood in primary total hip and knee arthroplasty: a prospective randomized clinical trial. Transfusion 2007 Mar;47(3):379-84.

New Moskowitz DM, McCullough JN, Shander A, Klein JJ, Bodian CA, Goldweit RS et al.The Impact of Blood Conservation on Outcomes in Cardiac Surgery: Is It Safe and Effective? Ann Thorac Surg. 2010;90:451-458

Munoz M, Leal-Noval R, Garcia-Erce JA. Intravenous iron in cardiac surgery. Semin Hematol 2006 Oct;43(4 Suppl 6):S39-42.

Raghavan M, Marik PE. Anemia, allogenic blood transfusion, and immunomodulation in the critically ill (review). Chest 2005 Jan; 127(1):295-307.

Rawn J.The silent risks of blood transfusion. Curr Opin Anaesthesiol. 2008 Oct;21(5):664-8.

Reddy SM, Talwar S, Velayoudam D, Gharde P, Mallick V, Jha RK, et al. Multi-modality blood conservation strategy in open-heart surgery: an audit. Interact Cardiovasc Thorac Surg 2009 Sep;9(3):480-2. Epub 2009 Jun 30.

NewRossaint R, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernández-Mondéjar E, et al.PDF Management of bleeding following major trauma: an updated European guideline. Crit Care. 2010 Apr 6;14(2):R52

Scott BH, Seifert FC, Grimson R. Blood transfusion is associated with increased resource utilisation, morbidity and mortality in cardiac surgery. Ann Card Anaesth. 2008 Jan-Jun;11(1):15-9.

Shander A, Hofmann A, Ozawa S, Javidroozi M. The true cost of red blood cell transfusion in surgical patients. ASH Poster Board III 127 (8 Dec. 2008)

Shander A, Goodnough LT. Objectives and limitations of bloodless medical care. Curr Opin Hematol 2006 Nov;13(6):462-70.

Shander A, Moskowitz D, Rijhwani TS. The safety and efficacy of "bloodless" cardiac surgery. Semin Cardiothorac Vasc Anesth 2005 Mar;9(1):53-63.

Shehata N, Wilson K, Mazer CD, Tomlinson G, Streiner D, Hebert P, Naglie G. The proportion of variation in perioperative transfusion decisions in Canada attributable to the hospital. Can J Anaesth. 2007 Nov;54(11):902-7.

Shehata N, Naglie G, Alghamdi AA, Callum J, Mazer CD, Hebert P, Streiner D, Wilson K. Risk factors for red cell transfusion in adults undergoing coronary artery bypass surgery: a systematic review. Vox Sang 2007 Jul;93(1):1-11.

Stowell CP. What happened to blood substitutes? Transfus Clin Biol 2005 Nov 30; [Epub ahead of print]

Tinmouth AT, McIntyre LA, Fowler RA. Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients. CMAJ 2008;178 49-57.

Virmani S, Tempe DK, Pandey BC, Cheema AS, Datt V, Garg M, et al. Acute normovolemic hemodilution is not beneficial in patients undergoing primary elective valve surgery. Ann Card Anaesth 2010 Jan-Apr;13(1):34-8.

Watson N, Taylor C. Allogeneic blood transfusion - the alternatives. Hospital Pharmacist 2000 May; 7(5): 118-123.

Whitson BA, Huddleston SJ, Savik K, Shumway SJ. Bloodless cardiac surgery is associated with decreased morbidity and mortality. J Card Surg 2007 Sep-Oct;22(5):373-8.

Wiedermann CJ. Hydroxyethyl starch--can the safety problems be ignored? Wien Klin Wochenschr. 2004 Sep 30;116(17-18):583-94

Zhao L, Wang B, You G, Wang Z, Zhou H. Effects of different resuscitation fluids on the rheologic behavior of red blood cells, blood viscosity and plasma viscosity in experimental hemorrhagic shock. Resuscitation 2008 Dec 5.

Zilberberg MD, Shorr AF. Effect of a restrictive transfusion strategy on transfusion-attributable severe acute complications and costs in the US ICUs: a model simulation. BMC Health Services Research 2007;7:138. (31 Aug. 2007)

The cost of blood: multidisciplinary consensus conference for a standard methodology. Transfus Med Rev 2005 Jan; 19(1):66-78.

Changes in blood supplies, regulations, and transfusion practice. Clinicians need to prepare for shortages now. (editorial) (Br Med J 2005 Feb 5;330:268-9)

Associations, Organizations, etc.


The Hemobag® - An Improved Way to Salvage Autologous Whole Blood in Surgery

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