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Perfusion - Important Articles

Blood storage impacts survival rate in cardiac surgery patients (20 Mar. 2008)

Koch CG, et al. Duration of red-cell storage and complications after cardiac surgery. N Engl J Med 2008 Mar 20;358(12):1229-39.

Adamson JW. New blood, old blood, or no blood (editorial). N Engl J Med 2008 Mar 20;358:1229-39.

Dennis Quaid recounts twins' drug ordeal (16 Mar. 2008)

China plant played role in Baxter heparin linked to 4 deaths (14 Feb. 2008)

Stents in the news

Heart bypass better than stents, study says (23 Jan. 2008)

CABG better than stents (MSNBC video)

Drug stents may not be worth it for many (2 Nov. 2007)

FDA plans new coated-stent restrictions (14 Dec. 2007)

Transfusion for anemia may contribute to early bypass mortality for women (Society of Thoracic Surgeons Meeting) (30 Jan. 2008)

Heart attack patients in U.S. are far more likely to receive blood transfusion than patients elsewhere (31 Dec. 2007)

Lower body temperatures increase blood loss during surgery (28 Jan. 2008)

Perioperative Blood Transfusion and Blood Conservation in Cardiac Surgery: The Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists Clinical Practice Guideline. Ann Thorac Surg 2007;83:S27-S86.

Blood protein offers clues to heart attack in seemingly healthy people (8 July 2007)

Drug coated stents linked to higher death risk for heart attack patients (4 Sept. 2007)

Drug-eluting and bare-metal stents equal In risk Of blood clots, heart attacks and death (28 Mar. 2007)

FDA revises labeling for Trasylol (Aprotinin injection) to strengthen safety warnings and limit usage of drug to specific situations (16 Dec. 2006)

U.S. strengthens warning for heart surgery drug

Webcast: Dr. David Taggart's lecture on stents vs CABG (Note: Real Player 10.5 required)

Doubt raised on drug-coated heart stents at 2006 World Cardiology Congress in Barcelona (4 Sept. 2006)

Riley JB, Samolyk KA, Lich BV, Moskowitz B, Shander A. Results from the Perfusion.com cardiac surgery hematocrit trend survey: observations and evidence-based recommendations. January 2006.

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Abdel-Rahman U, Ozaslan F, Risteski PS, Martens S, Moritz A, Al Daraghmeh A, et al. Initial experience with a minimized extracorporeal bypass system: is there a clinical benefit? Ann Thorac Surg 2005 Jul;80(1):238-43.

Arnestad JP, Hyllner M, Bengtson JP, Tylman M, Mollnes TE, Bengtsson A. Removal of activated complement from shed blood: comparison of high- and low-dilutional haemofiltration. Acta Anaesthesiol Scand 1998 Aug;42(7):811-5.

Aronson D, Dann EJ, Bonstein L, Blich M, Kapeliovich M, Beyar R, et al. Impact of red blood cell transfusion on clinical outcomes in patients with acute myocardial infarction. Am J Cardiol. 2008 Jul 15;102(2):115-9.

Banbury MK, Brizzio ME, Rajeswaran J, Lytle BW, Blackstone EH. Transfusion increases the risk of postoperative infection after cardiovascular surgery. J Am Coll Surg 2006 Jan; 202(1):131-8.

Barak M, Katz Y. Microbubbles: pathophysiology and clinical implications. Chest 2005 Oct;128(4):2918-32.

Baric D, Biocina B, Unic D, Sutlic Z, Rudez I, Vrca VB, Brkic K, Ivkovic M. Topical use of antifibrinolytic agents reduces postoperative bleeding: a double-blind, prospective, randomized study. Eur J Cardiothorac Surg. 2007 Jan 9; [Epub ahead of print]

Basran S, Frumento RJ, Cohen A, Lee S, Du Y, Nishanian E, et al. The association between duration of storage of transfused red blood cells and morbidity and mortality after reoperative cardiac surgery. Anesth Analg 2006 Jul;103(1):15-20.

Belway D, Rubens FD, Wozny D, Henley B, Nathan HJ. Are we doing everything we can to conserve blood during bypass? A national survey. Perfusion 2005 Sep;20(5):237-41.

Beohar N, et al. Off-label DES use causing high complication rates. JAMA 2007 May9;297(18): 1992-2000, 2001-2009.
- Win HK, er al. Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents. JAMA 2007 May9; 297(18): 2001-2009.

Boodhwani M, Williams K, Babaev A, Gill G, Saleem N, Rubens FD. Ultrafiltration reduces blood transfusions following cardiac surgery: a meta-analysis. Eur J Cardiothorac Surg 2006 Oct 12; [Epub ahead of print]

Bracey AW, Grigore AM, Nussmeier NA. Impact of platelet testing on presurgical screening and implications for cardiac and noncardiac surgical procedures. Am J Cardiol 2006 Nov 20;98(10S1):S25-S32.

Campbell JA, Holt DW, Shostrom VK, Durham SJ. Influence of intraoperative fluid volume on cardiopulmonary bypass hematocrit and blood transfusions in coronary artery bypass surgery. J Extra Corpor Technol 2008 Jun;40(2):99-108.

Chandler WL. Effects of hemodilution, blood loss, and consumption on hemostatic factor levels during cardiopulmonary bypass. J Cardiothorac Vasc Anesth 2005 Aug;19(4):459-67.

Cina CS, Clase CM. Coagulation disorders and blood product use in patients undergoing thoracoabdominal aortic aneurysm repair. Transfus Med Rev 2005 Apr;19(2):143-54.

Cotton BA, Guy JS, Morris JA Jr, Abumrad NN. The cellular, metabolic, and systemic consequences of aggressive fluid resuscitation strategies. Shock 2006 Aug;26(2):115-21.

Eising GP, Niemeyer M, G�nther T, Tassani P, Pfauder M, Schad H, Lange R. Does a hyperoncotic cardiopulmonary bypass prime affect extravascular lung water and cardiopulmonary function in patients undergoing coronary artery bypass surgery? Eur J Cardiothorac Surg 2001 Aug;20(2):282-9.

Eising GP, Pfauder M, Niemeyer M, Tassani P, Schad H, Bauernschmitt R, et al. Retrograde autologous priming: is it useful in elective on-pump coronary artery bypass surgery? Ann Thorac Surg 2003 Jan;75(1):23-7.

Feltracco P, Michieletto E, Barbieri S, Serra E, Rizzi S, Salvaterra F, Cillo U, Ori C. Microbiologic contamination of intraoperative blood salvaged during liver transplantation. Transplant Proc. 2007 Jul-Aug;39(6):1889-91.

Gerber DR. Transfusion of packed red blood cells in patients with ischemic heart disease. Crit Care Med. 2008 Apr;36(4):1068-74.

Goodnough LT, Shander A, Spivak JL, Waters JH, Friedman AJ, Carson JL, et al. Detection, evaluation, and management of anemia in the elective surgical patient. Anesth Analg 2005 Dec;101(6):1858-61.

Guo XY, Duan H, Wang JJ, Luo AL, Ye TH, Huang YG, et al. Effect of intraoperative using cell saver on blood sparing and its impact on coagulation function [Chinese]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2004 Apr;26(2):188-91.

Groeneveld ABJ, Evert K. Jansen EK, Verheij J. Mechanisms of pulmonary dysfunction after on-pump and off-pump cardiac surgery: a prospective cohort study. J Cardiothoracic Surg 2007; 2:11.

Guyton RA. Coronary artery bypass is superior to drug-eluting stents in multivessel coronary artery disease. Ann Thorac Surg 2006 Jun;81(6):1949-57.

Habib RH, Zacharias A, Schwann TA, Riordan CJ, Engoren M, Durham et al. Role of hemodilutional anemia and transfusion during cardiopulmonary bypass in renal injury after coronary revascularization: implications on operative outcome. Crit Care Med. 2005 Aug;33(8):1749-56.

Hannan EL, Racz MJ, Walford G, Jones RH, Ryan TJ, Bennett E, et al. Long-term outcomes of coronary-artery bypass grafting versus stent implantation. N Engl J Med 2005 May 26;352(21):2174-83.

Huang H, Yao T, Wang W, Zhu D, Zhang W, Chen H, Fu W. Continuous ultrafiltration attenuates the pulmonary injury that follows open heart surgery with cardiopulmonary bypass. Ann Thorac Surg. 2003 Jul;76(1):136-40.

Jani SM, Smith DE, Share D, Kline-Rogers E, Khanal S, O'Donnell MJ, Gardin J, Moscucci M. Blood transfusion and in-hospital outcomes in anemic patients with myocardial infarction undergoing percutaneous coronary intervention. Clin Cardiol 2007 Oct;30(10 Suppl 2):II49-56.

Jones TJ, Deal DD, Vernon JC, Blackburn N, Stump DA. How effective are cardiopulmonary bypass circuits at removing gaseous microemboli? J Extra Corpor Technol 2002 Mar;34(1):34-9.

Kamijo Y, Soma K, Sugimoto K, Tsuruta H, Ohwada T. The effect of a hemofilter during extracorporeal circulation on hemodynamics in patients with SIRS. Intensive Care Med 2000 Sep;26(9):1355-9.

Karkouti K, Wijeysundera DN, Beattie WS; Reducing Bleeding in Cardiac Surgery (RBC) Investigators. Risk associated with preoperative anemia in cardiac surgery: a multicenter cohort study. Circulation. 2008 Jan 29;117(4):478-84. Epub 2008 Jan 2.

Karkouti K, Djaiani G, Borger MA, Beattie WS, Fedorko L, Wijeysundera D, et al. Low hematocrit during cardiopulmonary bypass is associated with increased risk of perioperative stroke in cardiac surgery. Ann Thorac Surg 2005 Oct;80(4):1381-7.

Kestin AS, Valeri CR, Khuri SF, Loscalzo J, Ellis PA, MacGregor H, et al. The platelet function defect of cardiopulmonary bypass. Blood 1993 Jul 1; 82(1):107-17. [Medline abstract]

Khuri SF, Valeri CR, Loscalzo J, Weinstein MJ, Birjiniuk V, Healey NA, et al. Heparin causes platelet dysfunction and induces fibrinolysis before cardiopulmonary bypass. Ann Thorac Surg 1995 Oct;60(4):1008-14.

Kleisli T, Cheng W, Jacobs MJ, Mirocha J, Derobertis MA, Kass RM, et al. In the current era, complete revascularization improves survival after coronary artery bypass surgery. J Thorac Cardiovasc Surg 2005 Jun;129(6):1283-91.
- Restoring flow to all blocked areas of the heart improves 5-Year survival rate (Newswise, 21 June 2005)

Koch CG, Khandwala F, Li L, Estafanous FG, Loop FD, Blackstone EH. Persistent effect of red cell transfusion on health-related quality of life after cardiac surgery. Ann Thorac Surg 2006 Jul;82(1):13-20.

Koster A, Chew D, Merkle F, Gruendel M, Jurmann M, Kuppe H, Oertel R. Extracorporeal elimination of large concentrations of tirofiban by zero-balanced ultrafiltration during cardiopulmonary bypass: an in vitro investigation. Anesth Analg 2004 Oct;99(4):989-92.

Kuduvalli M, Oo AY, Newall N, Grayson AD, Jackson M, Desmond MJ, Fabri BM, Rashid A. Effect of peri-operative red blood cell transfusion on 30-day and 1-year mortality following coronary artery bypass surgery. Eur J Cardiothorac Surg 2005 Apr;27(4):592-8.

Kuduvalli M, Newall N, Stott A, Grayson AD, Fabri BM. Impact of avoiding cardiopulmonary bypass for coronary surgery on perioperative cardiac enzyme release and survival. Eur J Cardiothorac Surg 2006 Mar 4; [Epub ahead of print]
Kurusz M, Butler BD. Bubbles and bypass: an update. Perfusion 2004;19 (Suppl 1):S49-S55.

Lee LY, DeBois WJ, Krieger KH, Isom OW. Transfusion therapy and blood conservation. In: Cohn LH, Edmunds LH Jr, eds. Cardiac surgery in the adult. New York: McGraw-Hill, 2003:389-400. (Table of Contents)

Lee LY, DeBois W, Krieger KH, Girardi LN, Russo L, McVey J, et al. The effects of platelet inhibitors on blood use in cardiac surgery (review). Perfusion 2002 Jan;17(1):33-7

Legare JF, Hirsch G. Off-pump coronary artery bypass graft surgery is standard of care: Where do you stand? Can J Cardiol 2006 Nov;22(13):1107-10.

Legare JF, Buth KJ, Hirsch GM. Conversion to on pump from OPCAB is associated with increased mortality: results from a randomized controlled trial. Eur J Cardiothorac Surg 2005 Feb;27(2):296-301.

Levy JH, Tanaka KA, Steiner ME. Evaluation and management of bleeding during cardiac surgery. Curr Hematol Rep 2005 Sep;4(5):368-72.

Lilly KJ, O'Gara PJ, Treanor PR, Reardon D, Crowley R, Hunter C, et al. Cardiopulmonary bypass: it's not the size, it's how you use it! Review of a comprehensive blood-conservation strategy. J Extra Corpor Technol 2004 Sep;36(3):263-8.

Loeffelbein F, Zirell U, Benk C, Schlensak C, Dittrich S. High colloid oncotic pressure priming of cardiopulmonary bypass in neonates and infants: implications on haemofiltration, weight gain and renal function. Eur J Cardiothorac Surg. 2008 Sep;34(3):648-52. Epub 2008 Jul 30.

Mathew JP, Mackensen GB, Phillips-Bute B, Stafford-Smith M, Podgoreanu MV, Grocott HP, Hill SE, Smith PK, Blumenthal JA, Reves JG, Newman MF; Neurologic Outcome Research Group (NORG) of the Duke Heart Center. Effects of extreme hemodilution during cardiac surgery on cognitive function in the elderly. Anesthesiology 2007 Oct;107(4):577-84.

Martini J, Cabrales P, Tsai AG, Intaglietta M. Mechanotransduction and the homeostatic significance of maintaining blood viscosity in hypotension, hypertension and haemorrhage. J Intern Med 2006 Apr;259(4):364-72.

Morgan TO. Cost, quality, and risk: Measuring and stopping the hidden costs of coronary artery bypass graft surgery. Am J Health Syst Pharm 2005 Sep 14;62(18_Supplement_4):S2-S5.

Murphy GJ, Reeves BC, Rogers CA, Rizvi SI, Culliford L, Angelini GD. Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation. 2007 Nov 12; [Epub ahead of print]

Murphy GS, Szokol JW, Nitsun M, Alspach DA, Avram MJ, Vender JS, et al. Retrograde autologous priming of the cardiopulmonary bypass circuit: safety and impact on postoperative outcomes. J Cardiothorac Vasc Anesth 2006 Apr;20(2):156-61. Epub 2006 Jan 6.

Ngaage DL, Cowen ME, Griffin S, Guvendik L, Cale AR. Early neurological complications after coronary artery bypass grafting and valve surgery in octogenarians. Eur J Cardiothorac Surg. 2008 Feb 12 [Epub ahead of print]

Niemi TT, Suojaranta-Ylinen RT, Kukkonen SI, Kuitunen AH. Gelatin and hydroxyethyl starch, but not albumin, impair hemostasis after cardiac surgery. Anesth Analg 2006 Apr;102(4):998-1006.

Nollert G, Schwabenland I, Maktav D, Kur F, Christ F, Fraunberger P, et al. Miniaturized cardiopulmonary bypass in coronary artery bypass surgery: marginal impact on inflammation and coagulation but loss of safety margins. Ann Thorac Surg 2005 Dec;80(6):2326-32.
- Chaney MA. Review of Miniaturized cardiopulmonary bypass in coronary artery bypass surgery: marginal impact on inflammation and coagulation but loss of safety margins. (Feb. 2006)

Norman MJ, Sistino JJ, Acsell JR. The effectiveness of low-prime cardiopulmonary bypass circuits at removing gaseous emboli. J Extra Corpor Technol 2004 Dec;36(4):336-42.

Paiva P, Ferreira E, Antunes M. Bloodless open heart surgery: simple and safe. Rev Port Cardiol 2005 May;24(5):647-54.

Parolari A, Camera M, Alamanni F, Naliato M, Polvani GL, Agrifoglio M, et al. Systemic inflammation after on-pump and off-pump coronary bypass surgery: a one-month follow-up. Ann Thorac Surg 2007 Sep;84(3):823-8.

Prondzinsky R, Knupfer A, Loppnow H, Redling F, Lehmann DW, Stabenow I, et al. Surgical trauma affects the proinflammatory status after cardiac surgery to a higher degree than cardiopulmonary bypass. J Thorac Cardiovasc Surg 2005 Apr;129(4):760-6.

Rajagopalan S, Mascha E, Na J, Sessler DI. The effects of mild perioperative hypothermia on blood loss and transfusion requirement. Anesthesiology 2008 Jan;108(1):71-77.

Ranucci M, Biagioli B, Scolletta S, Grillone G, Cazzaniga A, Cattabriga I, Isgro G, Giomarelli P. Lowest hematocrit on cardiopulmonary bypass impairs the outcome in coronary surgery: An Italian multicenter study from the National Cardioanesthesia Database. Tex Heart Inst J 2006;33(3):300-305.

Ranucci M, Romitti F, Isgro G, Cotza M, Brozzi S, Boncilli A, Ditta A. Oxygen delivery during cardiopulmonary bypass and acute renal failure after coronary operations. Ann Thorac Surg 2005 Dec; 80(6):2213-20.

Rao SV. Implications of bleeding and blood transfusion in percutaneous coronary intervention. Rev Cardiovasc Med. 2007;8 Suppl 3:S18-26.

Rex S, Brose S, Metzelder S, de Rossi L, Schroth S, Autschbach R, Rossaint R, Buhre W. Normothermic beating heart surgery with assistance of miniaturized bypass systems: the effects on intraoperative hemodynamics and inflammatory response. Anesth Analg 2006 Feb;102(2):352-62.

Rinder CS, Smith MJ, Rinder HM, Cortright DN, Brodbeck RM, Krause JE, Smith BR. Leukocyte effects of C5a-receptor blockade during simulated extracorporeal circulation. Ann Thorac Surg 2007 Jan;83(1):146-52.

Rodriguez RA, Rubens F, Belway D, Nathan HJ. Residual air in the venous cannula increases cerebral embolization at the onset of cardiopulmonary bypass. Eur J Cardiothorac Surg 2006 Feb;29(2):175-80. Epub 2006 Jan 11.

Rosengart TK, DeBois W, O'Hara M, Helm R, Gomez M, Lang SJ, et al. Retrograde autologous priming for cardiopulmonary bypass: a safe and effective means of decreasing hemodilution and transfusion requirements. J Thorac Cardiovasc Surg 1998 Feb;115(2):426-38; discussion 438-9.

Rodriguez RA, Williams KA, Babaev A, Rubens F, Nathan HJ. Effect of perfusionist technique on cerebral embolization during cardiopulmonary bypass. Perfusion 2005 Jan;20(1):3-10.

Rubens FD, Boodhwani M, Mesana T, Wozny D, Wells G, Nathan HJ; Cardiotomy Investigators. The cardiotomy trial: a randomized, double-blind study to assess the effect of processing of shed blood during cardiopulmonary bypass on transfusion and neurocognitive function. Circulation 2007 Sep 11;116(11 Suppl):I89-97.

Russell JA, Navickis RJ, Wilkes MM. Albumin versus crystalloid for pump priming in cardiac surgery: meta-analysis of controlled trials. J Cardiothorac Vasc Anesth 2004 Aug;18(4):429-37.

Schroeder S, von Spiegel T, Stuber F, Hoeft A, Preusse CJ, Welz A, et al. Interleukin-6 enhancement after direct autologous retransfusion of shed thoracic blood does not influence haemodynamic stability following coronary artery bypass grafting. Thorac Cardiovasc Surg 2007 Mar;55(2):68-72.

Schroth M, Plank C, Meissner U, Eberle KP, Weyand M, Cesnjevar R, et al. Hypertonic-hyperoncotic solutions improve cardiac function in children after open-heart surgery. Pediatrics 2006 Jul;118(1):e76-e84. Epub 2006 Jun 2.

Sch�ttler J, Lutter G, B�ning A, Soltau D, Bein B, Caliebe D, et al. Is there really a clinical benefit of using minimized extracorporeal circulation for coronary artery bypass grafting? Thorac cardiovasc Surg 2008 Mar; 56(2): 65-70.

Scott BH, Seifert FC, Grimson R. Blood transfusion is associated with increased resource utilisation, morbidity and mortality in cardiac surgery. Ann Card Anaesth. 2008 Jan-Jun;11(1):15-9.

Scott EM, Buckland R. A systematic review of intraoperative warming to prevent postoperative complications. AORN J. 2006 May;83(5):1090-104, 1107-13.

Selnes OA, Grega MA, Bailey MM, Pham LD, Zeger SL, Baumgartner WA, McKhann GM. Cognition 6 years after surgical or medical therapy for coronary artery disease. Ann Neurol 2008 May 14;63(5):581-590. [Epub ahead of print]

Selnes OA, Grega MA, Borowicz LM Jr, Barry S, Zeger S, Baumgartner WA, et al. Cognitive outcomes three years after coronary artery bypass surgery: a comparison of on-pump coronary artery bypass graft surgery and nonsurgical controls. Ann Thorac Surg 2005 Apr;79(4):1201-9.

Shaffer KE, Pearman DT, Galen RS, Carville DG. A rapid platelet function assay used to regulate platelet transfusion prophylaxis following cardiopulmonary bypass surgery. J Extra Corpor Technol 2004 Jun;36(2):145-8.

Shapira OM, Aldea GS, Treanor PR, Chartrand RM, DeAndrade KM, Lazar HL, Shemin RJ. Reduction of allogeneic blood transfusions after open heart operations by lowering cardiopulmonary bypass prime volume. Ann Thorac Surg 1998 Sep;66(3):987-8.

Shehata N, Wilson K, Mazer CD, Tomlinson G, Streiner D, Hebert P, Naglie G. The proportion of variation in perioperative transfusion decisions in Canada attributable to the hospital. Can J Anaesth. 2007 Nov;54(11):902-7.

Sirvinskas E, Veikutiene A, Benetis R, Grybauskas P, Andrejaitiene J, Veikutis V, Surkus J. Influence of early re-infusion of autologous shed mediastinal blood on clinical outcome after cardiac surgery. Perfusion. 2007 Sep;22(5):345-52.

Slight RD, Demosthenous N, Nzewi OC, Soliman AR, McClelland DB, Mankad PS. The effect of gain in total body water on haemoglobin concentration and body weight following cardiac surgery. Heart Lung Circ. 2006 Aug;15(4):256-60.

Slight RD, Demosthenous N, Nzewi OC, Soliman AR, McClelland DB, Mankad PS. The effect of gain in total body water on haemoglobin concentration and body weight following cardiac surgery. Heart Lung Circ 2006 Jun 5; [Epub ahead of print]

Slight RD, Bappu NJ, Nzewi OC, McClelland DB, Mankad PS. Perioperative red cell, plasma, and blood volume change in patients undergoing cardiac surgery. Transfusion 2006 Mar;46(3):392-7.

Snyder-Ramos SA, M�hnle P, Weng YS, B�ttiger BW, Kulier A, Levin J, Mangano DT; Investigators of the Multicenter Study of Perioperative Ischemia; MCSPI Research Group. The ongoing variability in blood transfusion practices in cardiac surgery. Transfusion 2008 Apr 14 [Epub ahead of print]

Spiess BD, Ley C, Body SC, Siegel LC, Stover EP, Maddi R, et al. Hematocrit value on intensive care unit entry influences the frequency of q-wave myocardial infarction after coronary artery bypass grafting. J Thorac Cardiovasc Surg 1998 Sep;116(3):460-7.

Surgenor SD, DeFoe GR, Fillinger MP, Likosky DS, Groom RC, Clark C, et al. Intraoperative red blood cell transfusion during coronary artery bypass graft surgery increases the risk of postoperative low-output heart failure. Circulation 2006 Jul 4;114(1 Suppl):I43-8.

Syed A, Fawzy H, Farag A, Nemlander A. Comparison of pulmonary gas exchange in OPCAB versus conventional CABG. Heart Lung Circ 2004 Jun;13(2):168-72.

Taketani T, Motomura N, Toyokawa S, Kotsuka Y, Takamoto S. Beneficial effect of acute normovolemic hemodilution in cardiovascular surgery. Jpn J Thorac Cardiovasc Surg 2005 Jan;53(1):16-21.

Tanemoto K, Hamanaka S, Morita I, Masaki H. Platelet activity of residual blood remained in the cardiopulmonary bypass circuit after cardiac surgery. J Cardiovasc Surg (Torino). 2004 Feb;45(1):27-30.

Tircoveanu R, Van der Linden P. Hemodilution and anemia in patients with cardiac disease: what is the safe limit? Curr Opin Anaesthesiol 2008 Feb;21(1):66-70.

Tu JV, Bowen J, Chiu M, Ko DT, Austin PC, He Y, Hopkins R, Tarride JE, Blackhouse G, Lazzam C, Cohen EA, Goeree R. Effectiveness and safety of drug-eluting stents in Ontario. N Engl J Med 2007 Oct 4;357(14):1393-402.

van Dijk D, Diephuis JC, Nierich AP, Keizer AM, Kalkman CJ. Beating heart versus conventional cardiopulmonary bypass: the octopus experience: a randomized comparison of 281 patients undergoing coronary artery bypass surgery with or without cardiopulmonary bypass. Semin Cardiothorac Vasc Anesth. 2006 Jun;10(2):167-70.

Van der Linden P, Ickx BE. The effects of colloid solutions on hemostasis. Can J Anaesth 2006 Jun;53(6 Suppl):S30-9.

von Bormann B. Clinical aspects of packed red cell transfusion : Lessons learned from Jehovah's Witnesses? Anaesthesist. 2007 Mar 14. Epub ahead of print.

von Heymann C, Sander M, Foer A, Heinemann A, Spiess B, Braun J, Kramer M, et al. The impact of an hematocrit of 20% during normothermic cardiopulmonary bypass for elective low risk coronary artery bypass graft surgery on oxygen delivery and clinical outcome - a randomized controlled study [ISRCTN35655335].Crit Care. 2006 Apr 10;10(2):R58 [Epub ahead of print]

von Heymann C, Redlich U, Moritz M, Sander M, Vargas Hein O, Grubitzsch H, et al. Aspirin and clopidogrel taken until 2 days prior to coronary artery bypass graft surgery is associated with increased postoperative drainage loss. Thorac Cardiovasc Surg 2005 Dec;53(6):341-5.

Walpoth BH, Amport T, Schmid R, Kipfer B, Lanz M, Spaeth P, Kurt G, Althaus U. Hemofiltration during cardiopulmonary bypass: quality assessment of hemoconcentrated blood. Thorac Cardiovasc Surg 1994 Jun;42(3):162-9.

Wiedermann CJ. Hydroxyethyl starch--can the safety problems be ignored? Wien Klin Wochenschr. 2004 Sep 30;116(17-18):583-94.

Zelinka ES, Ryan P, McDonald J, Larson. Retrograde autologous prime with shortened bypass circuits decreases blood transfusion in high-risk coronary artery surgery patients. J Extra Corpor Technol 2004 Dec;36(4):343-7.

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The Hemobag^� - An Improved Way to Salvage Autologous Whole Blood in Surgery