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Ultrafiltration Literature & Information

Beckmann SR, Carlile D, Bissinger RC, Burrell M, Winkler T, Shely WW. Improved coagulation and blood conservation in the golden hours after cardiopulmonary bypass. J Extra Corpor Technol 2007 Jun;39(2):103-8.

PDF Moskowitz, DM, Klein JJ, Shander A, Perelman SI, McMurtry KA, Cousineau KM, Ergin MA. Use of the Hemobag® for modified ultrafiltration in a Jehovah’s Witness patient undergoing cardiac surgery. JECT 2006;38:265-70.

Samolyk KA, Beckmann SR, Bissinger RC. PDF A new practical technique to reduce allogeneic blood exposure and hospital costs while preserving clotting factors after cardiopulmonary bypass: the Hemobag®. Perfusion 2005 Oct;20(6):343–9.

Ultrafiltration's immediate and long-term benefits demonstrated in heart failure patients

Ultrafiltration: An innovative therapeutic approach to heart failure (Brigham and Women’s Hospital, Boston)


Arnestad JP, Hyllner M, Bengtson JP, Tylman M, Mollnes TE, Bengtsson A. Removal of activated complement from shed blood: comparison of high- and low-dilutional haemofiltration. Acta Anaesthesiol Scand 1998 Aug;42(7):811-5.

Belway D, Rubens FD, Wozny D, Henley B, Nathan HJ. Are we doing everything we can to conserve blood during bypass? A national survey. Perfusion 2005 Sep;20(5):237-41.

Boldt J, Kling D, Zickmann B, Jacobi M, Dapper F, Hempelmann G. Acute preoperative plasmapheresis and established blood conservation techniques. Ann Thorac Surg 1990 Jul;50(1):62-8.

Boldt J, Zickmann B, Fedderson B, Herold C, Dapper F, Hempelmann G. Six different hemofiltration devices for blood conservation in cardiac surgery. Ann Thorac Surg 1991 May;51(5):747-53.

Boldt J, Zickmann B, Czeke A, Herold C, Dapper F, Hempelmann G. Blood conservation techniques and platelet function in cardiac surgery. Anesthesiology 1991 Sep;75(3):426-32.

Boodhwani M, Williams K, Babaev A, Gill G, Saleem N, Rubens FD. Ultrafiltration reduces blood transfusions following cardiac surgery: a meta-analysis. Eur J Cardiothorac Surg 2006 Oct 12; [Epub ahead of print]

Campbell JA, Holt DW, Shostrom VK, Durham SJ. Influence of intraoperative fluid volume on cardiopulmonary bypass hematocrit and blood transfusions in coronary artery bypass surgery. J Extra Corpor Technol 2008 Jun;40(2):99-108.

Catala Bauset JC, de Andres Ibanez J, Grau Real F, Bengtsson A, Bengtson JP. Comparative study of two methods for salvaging red blood cells: centrifugation techniques (cell-saver) versus filtration through a 100,000-dalton filter. Rev Esp Anestesiol Reanim 1999 Oct;46(8):338-43.

Cheng W, Xiao YB, Zhong QJ. Application of modified ultrafiltration in infants undergoing cardiac surgery with cardiopulmonary bypass. Zhongguo Dang Dai Er Ke Za Zhi. 2008 Apr;10(2):152-4.

Coraim FI, Wolner E. Continuous hemofiltration for the failing heart (review). New Horiz 1995 Nov;3(4):725-31.

Coraim F, Pauser G, Stellwag F, Werner T, Ziegler W. Positive modification of hemodynamics in post cardiac surgery patients by hemofiltration. Improved method for the demonstration of myocardial depressant factor (MDF) in hemofiltrate. Anaesthesist 1985 May; 34(5):236-40.

Elahi MM, Yann Lim M, Joseph RN, Dhannapuneni RR, Spyt TJ.
Early hemofiltration improves survival in post-cardiotomy patients with acute renal failure. Eur J Cardiothorac Surg 2004 Nov;26(5):1027-31.


Honore' PM, Joannes-Boyau O, Merson L, Boer W, Piette V, Galloy AC, Janvier G. The big bang of hemofiltration: the beginning of a new era in the third millennium for extra-corporeal blood purification! Int J Artif Organs. 2006 Jul;29(7):649-59.

Huang H, Yao T, Wang W, Zhu D, Zhang W, Chen H, et al. Continuous ultrafiltration attenuates the pulmonary injury that follows open heart surgery with cardiopulmonary bypass. Ann Thorac Surg 2003 Jul;76(1):136-40. 

Journois D, Israel-Biet D, Pouard P, Rolland B, Silvester W, Vouhe P, etal. High-volume, zero-balanced hemofiltration to reduce delayed inflammatory response to cardiopulmonary bypass in children. Anesthesiology 1996 Nov;85(5):965-76.

Kamada M, Niibori K, Akimoto H, Yokoyama H, Tofukuji M, Iguchi A, et al. Efficacy of modified ultrafiltration in coronary artery bypass grafting. Kyobu Geka 2001 Jun;54(6):463-7. 

Kamijo Y, Soma K, Sugimoto K, Tsuruta H, Ohwada T. The effect of a hemofilter during extracorporeal circulation on hemodynamics in patients with SIRS. Intensive Care Med 2000 Sep;26(9):1355-9.

Kiziltepe U, Uysalel A, Corapcioglu T, Dalva K, Akan H, Akalin H.
Effects of combined conventional and modified ultrafiltration in adult patients. Ann Thorac Surg 2001 Feb;71(2):684-93.

Leyh RG, Bartels C, Joubert-Hubner E, Bechtel JF, Sievers HH. Influence of modified ultrafiltration on coagulation, fibrinolysis and blood loss in adult cardiac surgery. Eur J Cardiothorac Surg 2001 Feb;19(2):145-51.

Loeffelbein F, Zirell U, Benk C, Schlensak C, Dittrich S. High colloid oncotic pressure priming of cardiopulmonary bypass in neonates and infants: implications on haemofiltration, weight gain and renal function. Eur J Cardiothorac Surg. 2008 Sep;34(3):648-52. Epub 2008 Jul 30.

Luciani GB, Menon T,Vecchi B, Auriemma S, Mazzucco A. Modified ultrafiltration reduces morbidity after adult cardiac operations. A prospective, randomized clinical trial. Circulation 2001 Sep 18;104(12 Suppl 1):I253-9.

Morgan SH, Mansell MA, Thompson FD. Fluid removal by haemofiltration in diuretic resistant cardiac failure. Br Heart J 1985 Aug;54(2):218-9.

Nakamura Y, Masuda M, Toshima Y, Asou T, Oe M, Kinoshita K, et al. Comparative study of cell saver and ultrafiltration nontransfusion in cardiac surgery. Ann Thorac Surg 1990 Jun;49(6):973-8. 

Oliver WC Jr, Nuttall GA, Orszulak TA, Bamlet WR, Abel MD, Ereth MH, Schaff HV. Hemofiltration but not steroids results in earlier tracheal extubation following cardiopulmonary bypass: a prospective, randomized double-blind trial. Anesthesiology 2004 Aug;101(2):327-39.

Onoe M, Magara T, Nojima T, Yamamoto Y, Hong S, Uga H, et al. Application of modified ultrafiltration to cardiac surgery in adults. Kyobu Geka. 1999 Jun;52(6):451-4.

Onoe M, Magara T, Yamamoto Y, Nojima T. Modified ultrafiltration removes serum interleukin-8 in adult cardiac surgery. Perfusion. 2001 Jan;16(1):37-42.

Otaki M, Enmoto T, Oku H. Coronary bypass grafting for patients dependent on dialysis: modified ultrafiltration for perioperative management. ASAIO J 2003 Nov/Dec; 49(6): 650-4.

NewPérez-Vela J, Ruiz-Alonso E, Guillén-Ramirez F, García-Maellas M, Renes-Carreño E, Cerro-García M, et al. ICU outcomes in adult cardiac surgery patients in relation to ultrafiltration type. Perfusion. 2008 Mar;23(2):79-87.

Poullis M, Manning R, Haskard D, Taylor K. Reopro removal during cardiopulmonary bypass using a hemoconcentrator. J Thorac Cardiovasc Surg. 1999 May;117(5):1032-4.

Raman JS, Hata M, Bellomo R, Kohchi K, Cheung HL, Buxton BF. Hemofiltration during cardiopulmonary bypass for high risk adult cardiac surgery. Int J Artif Organs 2003 Aug;26(8):753-7. 

Ronco C, Tetta C, Lupi A, Galloni E, Bettini MC, Sereni L, et al. Removal of platelet-activating factor in experimental continuous arteriovenous hemofiltration. Crit Care Med 1995 Jan;23(1):99-107.

Rosenthal  K. Using ultrafiltration to treat heart failure. Nursing 2004 Apr: 34(4):17.

Sever K, Tansel T, Basaran M, Kafali E, Ugurlucan M, Ali Sayin O, et al. The benefits of continuous ultrafiltration in pediatric cardiac surgery. Scand Cardiovasc J 2004 Oct;38(5):307-11.

Skaryak LA, Kirshbom PM, DiBernardo LR, Kern FH, Greeley WJ, Ungerleider RM, et al. Modified ultrafiltration improves cerebral metabolic recovery after circulatory arrest. J Thorac Cardiovasc Surg 1995 Apr;109(4):744-51; discussion 751-2.

Smigla GR, Lawson DS, Shearer IR, Jaggers J, Milano C, Welsby I. An ultrafiltration technique for directly reinfusing residual cardiopulmonary bypass blood. J Extra Corpor Technol 2004 Sep; 36(3):231-4.

Solem JO, Stahl E, Kugelberg J, Steen S. Hemoconcentration by ultrafiltration during open-heart surgery. Scand J Thorac Cardiovasc Surg 1988;22(3):271-4.

Tallman RD, Dumond M, Brown D. Inflammatory mediator removal by zero-balance ultrafiltration during cardiopulmonary bypass. Perfusion 2002 Mar;17(2):111-5.

Tassani P, Richter JA, Eising GP, Barankay A, Braun SL, Haehnel CH, et al. Influence of combined zero-balanced and modified ultrafiltration on the systemic inflammatory response during coronary artery bypass grafting. J Cardiothorac Vasc Anest 1999 Jun;13(3):285-91. 

von Bormann B, Weidler B, Holleufer R, Muller-Wiefel H, Trobisch H. Alternative mechanical autotransfusion. Hemofiltration vs. hemoseparation [German]. Anasthesiol Intensivmed Notfallmed Schmerzther1992 Feb;27(1):11-7.

Walpoth BH, Amport T, Schmid R, Kipfer B, Lanz M, Spaeth P, Kurt G, Althaus U. Hemofiltration during cardiopulmonary bypass: quality assessment of hemoconcentrated blood. Thorac Cardiovasc Surg 1994 Jun;42(3):162-9.

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